Ryan P. Liegel, Ph.D.
Home Address:2733
Willard Ave.
Cincinnati, OH 45209
(608) 438-9868
ryanliegel@gmail.com
Education:
2013
Postdoctoral Fellow – Department of Cell Biology,
Neurobiology, and Anatomy; Medical College of Wisconsin (Milwaukee,
WI)
2006-2013
Ph.D. – Department of Cell Biology, Neurobiology, and
Anatomy; Medical College of Wisconsin (Milwaukee, WI)
2002-2006
B.S. – Biochemistry, Chemistry; University of Wisconsin -
Madison (Madison, WI)
Honors:
2012
Department of Cell Biology – Travel Award
2012
Outstanding poster presentation – Medical College of
Wisconsin Research Poster Day
2011
Renewed appointment to NEI T32 Vision science training grant
2010
Appointed to departmental NEI T32 Vision science training
grant
2010
Outstanding poster presentation – University of Wisconsin -
Madison ERI Symposium
2009
Best poster presentation – Midwest Eye Research Symposium,
Iowa City, Iowa
2009
International Mouse Genome Society – Travel Award
2009
Medical College of Wisconsin Graduate School – Travel Award
Publications:
2014
Park AK, Liegel RP, Ronchetti A, Ebert AD, Geurts A, Sidjanin DJ. “Targeted
disruption of Tbc1d20 with zinc-finger nucleases causes cataracts
and testicular anomalies in mice.” BMC Genetics. PMID: 25476608
2014
Liegel RP, Ronchetti A, Sidjanin DJ. “Alkylglyceronephosphate (AGPS)
deficient mice: models for rhizomelic chondrodysplasia punctate type
3 (RCDP3) malformation syndrome.” Molecular Genetics and Metabolism
Reports. PMID: 25197626
2013
Liegel RP*, Handley MT*, Ronchetti A, Brown S, Langemeyer L, Linford
A, Chang B, Morris-Rosendahl DJ, Carpanini S, Posmyk R, Harthill V,
Sheridan E, Abdel Salam GM, Terhal PA, Faravelli F, Accorsi P,
Giordano L, Pinelli L, Hartmann B, Ebert AD, Barr FA, Aligianis IA,
Sidjanin DJ. “Loss-of-function Mutations in TBC1D20 Cause Cataracts
and Male Infertility in blind-sterile Mice and Warburg Micro
Syndrome in Humans.” American
Journal of Human Genetics.
2013. PMID:
24239381
2011
Liang L, Liegel R, Endres B, Ronchetti A, Chang B, Sidjanin DJ. “Functional
analysis of the Hsf4(lop11) allele Responsible for
Cataracts in lop11 mice.”
Molecular Vision. PMID: 22162625
2011
Liegel R, Chang B, Dubielzig R, Sidjanin DJ. “Blind sterile 2 (bs2), a hypomorphic mutation in Agps, results in
cataracts and male sterility in mice.” Molecular Genetics and
Metabolism. PMID: 21353609
2010 Hassemer EL, Le Gall SM, Liegel R, McNally M, Chang B, Zeiss CJ, Dubielzig RD, Horiuchi K, Kimura T, Okada Y, Blobel CP, Sidjanin DJ “The waved with open eyelids (woe) locus is a hypomorphic mouse mutation in Adam17.” Genetics. PMID: 20194968
Abstracts presented:
2012
Poster: blind-sterile (bs) is a mutation in
Tbc1d20, a RabGTPase-activating protein, MCW Research poster day
2012
Poster: blind-sterile (bs) is a mutation in
Tbc1d20, a RabGTPase-activating protein, UW-Madison Eye Research
Institute Symposium, Madison, WI
2012
Talk: blind-sterile (bs) is a mutation in a member of the family of
RabGTPase activating proteins, International Symposium for Eye
Research, Berlin, Germany (1st author, but not presenting
author)
2012
Talk: Molecular mechanisms of cataract formation in
blind-sterile 2
(bs2) mice deficient in
Agps, International
Symposium for Eye Research, Berlin, Germany
2010
Poster: blind-sterile 2 (bs2) is a hypomorphic mutation in Agps, American
Society of Human Genetics meeting, Washington, DC
2010
Poster: The mouse locus
blind-sterile 2 (bs2) is a hypomorphic mutation in Agps,
UW-Madison Eye Research Institute Symposium, Madison, WI
2009
Talk: “bs2 is a hypomorphic mutation in Agps”, International Mammalian
Genome Conference, La Jolla, CA
2009
Poster: “The mouse locus
blind-sterile 2 (bs2) is a hypomorphic mutation in Agps, MCW Research Poster Day
2009
Poster: “The mouse locus
blind-sterile 2 (bs2) is a hypomorphic mutation in Agps, Midwest
Eye Research Symposium, Iowa City, IA
2008
Poster: Positional cloning of the
blind-sterile 2 (bs2)
locus in mice, American Society of Human Genetics meeting,
Philadelphia, PA
2008
Poster: “Positional cloning of the
blind-sterile 2 (bs2)
locus in mice, Midwest Developmental Biology conference, Iowa City,
IA
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